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Research Scientist I

Company: Charles River
Location: Newark
Posted on: June 8, 2021

Job Description:

Research Scientist I

Req ID #: 103651


Newark, DE, US, 19711

For nearly 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.isabled/Vet

Job Summary

We are seeking an experienced Research Scientist I for our Microbial Solutions site in Newark, DE.

The Research Scientist I will be responsible for contributing to the scientific growth of the Accugenix business. They will be the primary developer of the reference libraries for improving performance, accuracy, precision, and robustness of the Accugenix identification platforms including, but not limited to, 16S and ITS2 rDNA Sanger sequencing, MALDI-TOF mass spectrometry, and protein-coding gene sequencing.

The following are responsibilities related to the Research Scientist 1 position:

* Curate, test and document new or modified library entries for Accugenix supported bacterial and fungal libraries following approved SOPs. * Follow IJSEM and other journals for the publication of new species of interest. When new organisms are found, check to see if they represent new valid species that could be included in the library. * Maintain Accugenix type strain culture collection used in library development and testing. * Evaluate alternative protein-coding sequencing targets for species/subspecies ID and for strain typing. * Participate in the development of alternative approaches to new or modified assays that will lead to improved performance and quality and can be effectively automated. * Evaluate feasibility of alternative approaches, and with the management team, select approach that shows the most promise considering potential for improvement, material and labor cost of assay, time to final customer report and development expenses and time. * Develop selected approach further by evaluating robustness, tradeoffs, and design process steps; test with known strains and customer samples and write development report detailing benefits and costs of implementing in the lab. * Collaborate with lab manager to implement new or modified library development processes, corresponding assays, provide sources of new materials, SOPs, training and any other support needed to install and validate the change. * Provide technical training to customers as needed. * Represent company as a speaker at customer sites, seminars and conferences. * Provide support for trouble shooting identification report issues and to data review and customer support for the interpretation of customer sample results. * Provide support for trouble shooting assay related problems related to sequencing and MALDI. * May supervise direct reports and be responsible for personnel management activities such as: scheduling, personnel actions (hiring, promotions, transfer, etc.), training and development, providing regular direction and feedback on performance, disciplinary actions and preparing and delivering annual performance and salary reviews. * Observe established safety guidelines and maintain effectiveness of the department. * Adhere to work procedures and processes that support company and departmental standards, procedures and strategic directives. * Ensure that all regulatory and GMP compliance requirements are met and adhered to in the development process. * Perform all other related duties as assigned.


* Ph.D. in Microbiology, Molecular Biology or related discipline preferred. M.S. in Microbiology, Molecular Biology or related discipline may be considered. * One or more years of related laboratory experience in Molecular Biology, Microbiology, or related field post completion of Ph.D., or five or more years of related experience post completion of M.S degree. Specific experience in bacterial and/or fungal taxonomy, molecular systematics, microbial identification, Sanger sequencing, and/or MALDI-TOF is required. Knowledge of bioinformatics tools is a plus.

About Microbial Solutions

Our Microbial Solutions business group has a comprehensive portfolio of endotoxin testing, microbial detection and microbial identification products and services is unlike any other, and has been purposefully designed to meet the complex and ever-changing needs of the industry. We help clients to ensure product safety and quality with easy-to-use yet robust testing solutions that satisfy regulatory requirements, support critical decision making and improve operational efficiencies.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 14,000 employees within 80 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2018, revenue increased by 22% to $2.27 billion from $1.86 billion in 2017.

At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2018.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - M/F/Disabled/Vet

Nearest Major Market: Philadelphia

Job Segment: Biotech, Microbiology, Scientific, Research Scientist, Science, Engineering, Research

Keywords: Charles River, Newark , Research Scientist I, Other , Newark, Delaware

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